Fact Snapshot
- Paper: Ultrasonic assisted synthesis of adenosine triphosphate capped manganese-doped ZnS quantum dots for selective room temperature phosphorescence detection of arginine and methylated arginine in urine based on supramolecular Mg2+–adenosine triphosphate–arginine ternary system
- Equipment: XH-300 series
- Source: Talanta, 2021
- Research direction: Research application
- Core conditions: Ultrasonic power 1000 W and Time 7 min / 30 min / 10 min
- Key results: Recovery -100%, Dilution enables quantification 50-fold, and Phosphorescence intensity 2.3-fold
Research Abstract
Ultrasonic assisted synthesis of adenosine triphosphate capped manganese-doped ZnS quantum dots for selective room temperature phosphorescence detection of arginine and methylated arginine in urine based on supramolecular Mg2+–adenosine triphosphate–arginine ternary system was published in Talanta (2021) and is indexed as a SoarNova / Xianghu Q1 application case for XH-300 series. The source record connects it with Research application. Core operating conditions include Ultrasonic power 1000 W and Time 7 min / 30 min / 10 min. Key reported results include Recovery -100%, Dilution enables quantification 50-fold, and Phosphorescence intensity 2.3-fold.
Research Background and Problem
Equipment Use and Experimental Conditions
| Item | Parameter |
|---|---|
| Ultrasonic power | 1000 W |
| Time | 7 min / 30 min / 10 min |
Key Result
| Metric | Result |
|---|---|
| Recovery | -100% |
| Dilution enables quantification | 50-fold |
| Phosphorescence intensity | 2.3-fold |
Evidence Details
1-10 mM：DP = 171.3CArginine + 158.7，R2 = 0.992
10-35 mM：DP = 50CArginine + 1349.5，R2 = 0.997
Typically, 5 mL of 0.04 M ATP, 5 mL of 0.1 M Zn(CH3COO)2 and 0.2 mL of 0.1 M Mn(CH3COO)2 were mixed with 40 mL ultrapure water in a 100 mL three-necked flask under ultrasonication at a power of 1000 W under argon for 7 min.
5 mL of 0.1 M Na2S·9H2O was then added and the mixture was subjected ultrasonification at a power of 1000 W for 30 min to yield highly luminescent ATP-capped Mn-doped ZnS QDs.
A 50-fold dilution of urine was found sufficient to obtain a quantitative recovery (94-100%) of spiked arginine and to use a simple aqueous standard solution for the accurate quantification of arginine and methylated arginine.
The developed ATP-capped Mn-doped ZnS QDs gave the detection limit (LOD) (3 s) of 0.23 mM for arginine with the relative standard deviation of 1.7% for eleven replicate detections of 10 mM arginine.
The present ultrasonic assisted approach not only provided a much faster synthesis (37 min versus 170 min), but also gave 2.3 times higher phosphorescence intensity than the traditional method.
Time: 7 min / 30 min / 10 min
The ultrasonic assisted synthesis of ATP-capped Mn-Doped ZnS QDs was carried out on XiangHu Microwave-ultrasound reactor (XH-300A, XiangHu Science and Technology Development Co. Ltd, Beijing, China).
Ultrasonic-method evidence: source values include 2 h, 2.3 fold.
The HRTEM images reveal spherical shape of ATP-capped Mn-doped ZnS QDs with the diameters of 3-5 nm.
Additional source evidence: source values include 300 nm, 595 nm.
Additional source evidence: source values include 5 min, 63%.
Recovery: -100%
Mechanism / Method Highlights
- Method context: Ultrasonic power 1000 W and Time 7 min / 30 min / 10 min.
- Release-kinetics evidence: 1-10 mM: DP = 171.3CArginine + 158.7, R2 = 0.992
- Release-kinetics evidence: 10-35 mM: DP = 50CArginine + 1349.5, R2 = 0.997
- Source evidence: Typically, 5 mL of 0.04 M ATP, 5 mL of 0.1 M Zn(CH3COO)2 and 0.2 mL of 0.1 M Mn(CH3COO)2 were mixed with 40 mL ultrapure water in a 100 mL three-necked flask under ultrasonication at a power of 1000 W under argon for 7 min
- Reported outcome: Recovery -100%, Dilution enables quantification 50-fold, and Phosphorescence intensity 2.3-fold.
Application Value
- Provides a peer-reviewed SoarNova / Xianghu Q1 application case for XH-300 series.
- Supports English discovery around Research application.
- Preserves quantitative result evidence: Recovery -100%, Dilution enables quantification 50-fold, and Phosphorescence intensity 2.3-fold.
- Maintains source-level evidence details: Release-kinetics evidence: 1-10 mM: DP = 171.3CArginine + 158.7, R2 = 0.992, Release-kinetics evidence: 10-35 mM: DP = 50CArginine + 1349.5, R2 = 0.997, Source evidence: Typically, 5 mL of 0.04 M ATP, 5 mL of 0.1 M Zn(CH3COO)2 and 0.2 mL of 0.1 M Mn(CH3COO)2 were mixed with 40 mL ultrapure water in a 100 mL three-necked flask under ultrasonication at a power of 1000 W under argon for 7 min, and Source evidence: 5 mL of 0.1 M Na2S·9H2O was then added and the mixture was subjected ultrasonification at a power of 1000 W for 30 min to yield highly luminescent ATP-capped Mn-doped ZnS QDs.
Related Equipment
FAQ
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Which publication does this case come from?
Ultrasonic assisted synthesis of adenosine triphosphate capped manganese-doped ZnS quantum dots for selective room temperature phosphorescence detection of arginine and methylated arginine in urine based on supramolecular Mg2+–adenosine triphosphate–arginine ternary system
Talanta, 2021
DOI: 10.1016/j.talanta.2012.03.055