Fact Snapshot
- Paper: Optimization of microwave-assisted extraction using response surface methodology and the potential anti-diabetic efficacy of Nigella glandulifera Freyn determined using the spectrum–effect relationship
- Equipment: XH-300 series
- Source: Industrial Crops and Products, 2020
- Research direction: Research application
- Core conditions: Temperature 70 °C / 80 °C / 66.38 °C, Microwave power 350 W, and Time 25 min / 40 min / 35 min
- Key results: Yield 2.69%, Measured extraction yield 16.82%, Measured extraction yield 53.03%, and Measured extraction yield 67.05%
Research Abstract
Optimization of microwave-assisted extraction using response surface methodology and the potential anti-diabetic efficacy of Nigella glandulifera Freyn determined using the spectrum–effect relationship was published in Industrial Crops and Products (2020) and is indexed as a Xianghu Q1 application case for XH-300 series. The source record connects it with Research application. Core operating conditions include Temperature 70 °C / 80 °C / 66.38 °C, Microwave power 350 W, and Time 25 min / 40 min / 35 min. Key reported results include Yield 2.69%, Measured extraction yield 16.82%, Measured extraction yield 53.03%, and Measured extraction yield 67.05%.
Research Background and Problem
Equipment Use and Experimental Conditions
| Item | Parameter |
|---|---|
| Temperature | 70 °C / 80 °C / 66.38 °C |
| Microwave power | 350 W |
| Time | 25 min / 40 min / 35 min |
Key Result
| Metric | Result |
|---|---|
| Yield | 2.69% |
| Measured extraction yield | 16.82% |
| Measured extraction yield | 53.03% |
| Measured extraction yield | 67.05% |
Evidence Details
The defatted dried seeds (10 g) were mixed with 70% ethanol (v/v, 100 mL) in a vessel and then irradiated with a microwave power setting of 350 W at 70 °C for 25 min.
After passing through the AB-8 resin, the yield of the effective components from the seeds was 2.69%, with IC50 values for aldose reductase activity, DPPH, ABTS and PTP1B activity of 131.21 μg/mL, 64.31 μg/mL, 51.36 μg/mL, and 2.96 μg/mL, respectively.
Additional source evidence: source values include 1:19.52, 70.48%, 35 min, 66.38 °C, 16.82%, 15.62%.
The optimal extraction method was as follows; solid-to-liquid ratio of 1:20 g/mL, ethanol concentration of 70%, extraction time of 35.00 min, and extraction temperature of 66 °C.
Additional source evidence: source values include 350 W, 70 °C, 25 min. Entities: XH-300A.
AR inhibition rate 59.04% 67.05%
Antioxidant rate 47.23% 53.03%
Temperature: 70 °C / 80 °C / 66.38 °C
Time: 25 min / 40 min / 35 min
Additional source evidence: source values include 1:5, 1:30.
Additional source evidence: source values include 40%, 90%.
Mechanism / Method Highlights
- Method context: Temperature 70 °C / 80 °C / 66.38 °C, Microwave power 350 W, and Time 25 min / 40 min / 35 min.
- Equipment evidence: The defatted dried seeds (10 g) were mixed with 70% ethanol (v/v, 100 mL) in a vessel and then irradiated with a microwave power setting of 350 W at 70 °C for 25 min
- Source evidence: After passing through the AB-8 resin, the yield of the effective components from the seeds was 2.69%, with IC50 values for aldose reductase activity, DPPH, ABTS and PTP1B activity of 131.21 μg/mL, 64.31 μg/mL, 51.36 μg/mL, and 2.96 μg/mL, respectively
- Additional source evidence: source values include 1:19.52, 70.48%, 35 min, 66.38 °C, 16.82%, 15.62%
- Reported outcome: Yield 2.69%, Measured extraction yield 16.82%, Measured extraction yield 53.03%, and Measured extraction yield 67.05%.
Application Value
- Provides a peer-reviewed SoarNova / Xianghu Q1 application case for XH-300 series.
- Supports English discovery around Research application.
- Preserves quantitative result evidence: Yield 2.69%, Measured extraction yield 16.82%, Measured extraction yield 53.03%, and Measured extraction yield 67.05%.
- Maintains source-level evidence details: Equipment evidence: The defatted dried seeds (10 g) were mixed with 70% ethanol (v/v, 100 mL) in a vessel and then irradiated with a microwave power setting of 350 W at 70 °C for 25 min, Source evidence: After passing through the AB-8 resin, the yield of the effective components from the seeds was 2.69%, with IC50 values for aldose reductase activity, DPPH, ABTS and PTP1B activity of 131.21 μg/mL, 64.31 μg/mL, 51.36 μg/mL, and 2.96 μg/mL, respectively, Additional source evidence: source values include 1:19.52, 70.48%, 35 min, 66.38 °C, 16.82%, 15.62%, and Abstract evidence: The optimal extraction method was as follows; solid-to-liquid ratio of 1:20 g/mL, ethanol concentration of 70%, extraction time of 35.00 min, and extraction temperature of 66 °C.
Related Equipment
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Optimization of microwave-assisted extraction using response surface methodology and the potential anti-diabetic efficacy of Nigella glandulifera Freyn determined using the spectrum–effect relationship
Industrial Crops and Products, 2020
DOI: 10.1016/j.indcrop.2020.112592